It is located in the University City section of Philadelphia. Founded in 1765, the Perelman School of Medicine is the oldest medical school in the United States. Today, it is a major center of biomedical research and education, and it is widely regarded as one of the country's top medical schools. Penn Med consistently ranks among the highest recipients of NIH research awards, and currently ties for 6th on U.S. News & World Report's "Best Medical Schools”.
The school of medicine was founded by Dr. John Morgan, a graduate of the College of Philadelphia (A.B. 1757) and the University of Edinburgh Medical School (M.D. 1763). In 1765, after training in Edinburgh and other European cities, Dr. Morgan returned to Philadelphia. With fellow University of Edinburgh Medical School graduate Dr. William Shippen Jr., Morgan persuaded the Trustees of the University of Pennsylvania to found the first medical school in the Original Thirteen Colonies.
Only months before the medical school was created, Morgan delivered an address to the Trustees and the citizens of Philadelphia, "Upon the Institution of Medical Schools in America" during which he expressed his desire for the new medical school to become a model institution.
According to wikipedia